65 questions · 47 sources · 0 syntheses
History of Medicine
The evolution of medical knowledge and practice.
Source-derived questions
Questions extracted from the papers in this topic, excluding the curated questions above.
- By what point in 1943 could penicillin output supply the entire Allied armed forces, and how did that change wound treatment in the war?
- How accurate was MYCIN at diagnosing blood infections compared to human clinicians?
- How did Alvin Roth redesign the National Resident Matching Program to eliminate last-minute scrambles?
- How did Donald Unger design his decades-long self-experiment to test whether knuckle-cracking causes arthritis?
- How did Fibiger's death in 1928 shape how his mistaken discovery came to be remembered?
- How did Finsen's own illness shape his interest in the biological effects of sunlight?
- How did Hofmann accidentally absorb LSD through his skin on 16 April 1943, and what did he record about the experience?
- How did Landsteiner's 1930 Nobel Prize help standardize blood typing practice across hospitals?
- How did a type 1 diabetes diagnosis change from a death sentence measured in months to a manageable condition?
- How did the Royal Army Medical Corps's 1916 transfusion become the founding act of blood banking?
- How did the audience react when Alzheimer first presented his findings to fellow psychiatrists?
- How did the availability of mass-produced penicillin change survival odds for wounded soldiers by D-Day?
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- How did the urgency of wartime casualties drive the industrialization of penicillin production in the United States?
- How did transplantation move from a procedure only possible between twins to a routine intervention performed a quarter million times a year?
- How quickly did diphtheria antitoxin move from laboratory discovery to manufactured treatment for children?
- How were diabetics treated with insulin before recombinant bacterial production became possible?
- What complications did Barney Clark experience while living with the artificial heart, and how long did he survive?
- What did Fleming's initial tests of crude mould extract on infected surfaces and cultures actually demonstrate?
- What did Horiuchi learn about patient comfort and positioning during colonoscopy from self-experimentation?
- What did William B. Bean's thirty-five-year daily record reveal about how fingernail growth changes with season and age?
- What did Yoshiro Nakamatsu do every day for over thirty-four years as part of his self-experiment?
- What did the miasma theory of malaria claim, and where did that idea originally come from?
- What did the study confirm or correct about prior anatomical assumptions?
- What disease was Niels Finsen trying to treat with concentrated ultraviolet light?
- What effect did standardized blood typing have on survival rates in the following decade's war wounded?
- What everyday medical technologies depend on a correct understanding of osmosis?
- What happened to Forssmann's career after his self-experiment became known?
- What happened when a television programme tried to observe her going without food and water?
- What historical text pointed Tu Youyou toward sweet wormwood as a fever remedy?
- What impact did mass-produced penicillin have on Allied casualties by D-Day in 1944?
- What is Otodectes cynotis, and why did Robert Lopez want to know what an infestation felt like firsthand?
- What logistical problem stood between penicillin's proven clinical effect and treating soldiers at scale?
- What made Hofmann's laboratory notes from Bicycle Day notable as a scientific document?
- What made Oliver Sacks' clinical case studies different from conventional neurology writing?
- What modern cardiac procedures trace their lineage back to Forssmann's original catheter?
- What other scientists have famously experimented on themselves to prove a medical point, like Barry Marshall or Werner Forssmann?
- What preventive measures existed for yellow fever before Theiler's 17D vaccine?
- What prompted a general practitioner to investigate a question as casual as whether older men have bigger ears?
- What substances did Bærheim and Sandvik test on leeches to study their feeding preferences?
- What symptoms did Lopez record after transferring feline ear mites into his own ear canal?
- What was the prevailing medical explanation for peptic ulcers before Warren and Marshall's work?
- What was the subject of Busch and Starling's award-winning medical literature review?
- Where did the Detroit physicians find the historical precedent for using salted pork as a nasal pack?
- Where was Vatle's study of sample containers published, and what field did it fall under?
- Which substance appeared to discourage leeches from feeding, and why might that matter clinically?
- Who were the first subjects of Cournand's catheterization experiments?
- Why did Akira Horiuchi choose to perform colonoscopies on himself rather than on volunteers?
- Why did Barry Marshall decide to drink a culture of Helicobacter pylori himself?
- Why did Mack treat the consistency of abductees' accounts as significant clinical evidence?
- Why did Werner Forssmann perform cardiac catheterization on himself rather than a patient in 1929?
- Why did framing nuclear war as a medical triage problem prove more persuasive than strategic military analysis?
- Why did medical journals remain skeptical of the H. pylori theory for years after the experiment?
- Why does no other dataset like Bean's exist in the biological literature on nail growth?
- Why does the medical literature require documentation of unusual transmission cases, even ones that seem more comic than clinical?
- Why had willow bark been used as a folk remedy for thousands of years before anyone understood its molecular mechanism?
- Why is a systematic review of unusual emergency-room cases genuinely useful to surgeons?
- Why might rectal oxygen administration matter in settings where ventilators are scarce or unavailable?
- Why was Howard Florey's Oxford team growing penicillin mould in bedpans and milk churns in 1941?
- Why was cutting into the nervous system to see what stopped working an unreliable way to study it?
- Why was direct donor-to-recipient transfusion such a logistical bottleneck before 1916?
- Why was pre-transfusion blood typing still inconsistent in hospitals thirty years after its discovery?
- Why was the idea of a cancer-causing infectious agent so foreign to medical orthodoxy in 1909?
- Why was the original ECG apparatus so impractical, and how did the technology change afterward?
- Why was wound infection historically a bigger killer of soldiers than combat wounds themselves?
- Why would no ethics board or funding body have approved this study if it had been proposed formally?
Sources
- 2.3 million doses of penicillin prepared for D-Day invasion
- Albert Hofmann synthesizes LSD
- Alois Alzheimer's first description of Alzheimer's disease
- Blood group typing advances transfusion medicine
- Boyer-Cohen gene cloning in bacteria demonstrated
- Death of Oliver Sacks
- First permanent artificial heart implanted in a human
- First successful clinical tests of penicillin begin
- First successful transfusion of stored blood
- Ig Nobel Prize in Anatomy
- Ig Nobel Prize in Biology
- Ig Nobel Prize in Entomology
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- Ig Nobel Prize in Literature
- Ig Nobel Prize in Literature
- Ig Nobel Prize in Literature
- Ig Nobel Prize in Medical Education
- Ig Nobel Prize in Medicine
- Ig Nobel Prize in Medicine
- Ig Nobel Prize in Medicine
- Ig Nobel Prize in Medicine
- Ig Nobel Prize in Nutrition
- Ig Nobel Prize in Physiology
- Ig Nobel Prize in Psychology
- Ig Nobel Prize in Public Health
- Lasker Award for Basic Medical Research
- Nobel Peace Prize
- Nobel Prize in Chemistry
- Nobel Prize in Physiology or Medicine
- Nobel Prize in Physiology or Medicine
- Nobel Prize in Physiology or Medicine
- Nobel Prize in Physiology or Medicine
- Nobel Prize in Physiology or Medicine
- Nobel Prize in Physiology or Medicine
- Nobel Prize in Physiology or Medicine
- Nobel Prize in Physiology or Medicine
- Nobel Prize in Physiology or Medicine
- Nobel Prize in Physiology or Medicine
- Nobel Prize in Physiology or Medicine
- Nobel Prize in Physiology or Medicine
- Penicillin mass production begins in the United States