4 questions · 1 source · 0 syntheses
Cryo-Electron Microscopy
Imaging frozen biomolecules to near-atomic resolution.
Source-derived questions
Questions extracted from the papers in this topic, excluding the curated questions above.
- How did Joachim Frank turn thousands of blurry electron microscope images into one sharp structure?
- What does it mean to vitrify water, and why does that matter for imaging a protein with electrons?
- What triggered the 'resolution revolution' in cryo-EM after decades of finicky, indistinct images?
- Why did many proteins, especially membrane proteins, resist the older method of crystallisation for imaging?