- Why does a lack of folic acid cause red blood cells to grow abnormally large?
Cell Cycle and Division
The regulated process of cell growth and division.
- What molecular machinery coordinates the timing of DNA duplication and cell division?
- What did Leland Hartwell discover about cell-cycle checkpoint genes working in yeast?
- How did Yoshio Masui's maturation-promoting factor and Paul Nurse's cyclin-dependent kinase together explain what drives a cell into division?
- Why is the loss of cell-cycle control considered essentially what cancer is?
- What is a cell cycle checkpoint and what does it prevent from happening?
- How did Tim Hunt discover cyclins, the proteins that rise and fall with each cell division?
- What role does the kinase cdc2 play in moving a cell from one phase of division to the next?
- Why is cancer often described as a disease of failed checkpoints?