- What gas mixture did Stanley Miller use to simulate early Earth's atmosphere, and why?
- How did the Miller-Urey result shift the study of the origin of life from philosophy to experimental chemistry?
- Why does later uncertainty about early Earth's actual atmospheric composition complicate the experiment's conclusions?
Origin of Life
Theories and evidence for how life began.
- How did Schrödinger's 1944 book What Is Life? influence Francis Crick's move into biology?
- How did Cech's discovery of self-splicing RNA support the idea of an early 'RNA world'?
- Why did finding an RNA enzyme give the RNA world hypothesis its first real experimental support?
- What organic molecules did Philae detect during its sixty hours of operation, and why did they matter to origin-of-life questions?
- What is the RNA World hypothesis, and what circular problem about proteins and RNA does it try to resolve?
- Why has building an RNA molecule that can copy a version of itself proven so experimentally difficult?